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Singh, Jitendra
- A Case Report of Sildenafil Poisoning and an Approach to Management
Abstract Views :856 |
PDF Views:22
Authors
Affiliations
1 Department of Psychiatry, King George Medical University, Lucknow - 226 003, Uttar Pradesh, IN
2 Department of Medicine, King George Medical University, Lucknow - 226 003, Uttar Pradesh, IN
3 Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - 226014, IN
1 Department of Psychiatry, King George Medical University, Lucknow - 226 003, Uttar Pradesh, IN
2 Department of Medicine, King George Medical University, Lucknow - 226 003, Uttar Pradesh, IN
3 Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - 226014, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 22, No 2 (2015), Pagination: 126-128Abstract
Sildenafil is Food and Drug Administration approved medication for management of erectile dysfunction which was initially used for pulmonary hypertension. We hereby report a case of 32-year-old male suffering from erectile dysfunction who attempted suicide following altercation with his wife by consuming around 30 tablets of 100 mg sildenafil. He was admitted to medical emergency unit with complaints of flushing, multiple episodes of vomiting, hypotension, tachycardia, dehydration, and priapism. Patient was managed with intravenous fluids and supportive management. Subsequently patient was follow-up in psychiatry outpatient department and responded well.Keywords
Overdose, Hypotension, Priapism, Sildenafil Toxicity.References
- James SB, Alcott SV, Ruiz P. Phoshphodiesrease-5 inhibitor. Kaplan and Sadock’s Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. 11th ed. New Delhi: Wolters Kluwer Pvt Ltd. 2007; 1008–10.
- Tripathi KD. Androgens and drugs for erectile dysfunction. In: Tripathi KD, editor. Essentials of Medical Pharmacology. 6th ed. New Delhi: Jaypee Brothers Medical Publishers. 2008; 296–305.
- McVary KT. Sexual dysfunction. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J et al. editors. Harrison’s Principles of Internal Medicine. 18th ed. New York: McGraw Hill. 2012; 374–80.
- Daghfous R, El Aidli S, Zaiem A, Loueslati MH, Belkahia C. Sildenafil-associated hepatotoxicity. Am J Gastroenterol. 2005; 100:1895–6.
- Wills BK, Albinson C, Wahl M, Clifton J. Sildenafil citrate ingestion and prolonged priapism and tachycardia in a pediatric patient. Clin Toxicol (Phila). 2007; 45:798–800.
- Oh DJ. Sildenafil overdose can cause rhabdomyolysis and subjective visual perception changes. Nephrology (Carlton). 2014; 19:258.
- Sadeghi-Nejad H, Dogra V, Seftel AD, Mohamed MA. Priapism. Radiol Clin North Am. 2004; 42:427–43.
- Hung DZ, Yang DY. Sildenafil overdose in a female patient. J Toxicol Clin Toxicol. 2001; 39:423–4.
- Krenzelok EP. Sildenafil: Clinical toxicology profile. J Toxicol Clin Toxicol. 2000; 38:645–51.
- Effect of Plant Growth Regulators and Fertigation on Growth of Pomegranate Cv. Sinduri under High Density Planting System in Sub-humid Plains of South Eastern Rajasthan
Abstract Views :104 |
PDF Views:0
Authors
Mahaveer Suman
1,
M. C. Jain
2,
Jitendra Singh
1,
R. R. Meena
3,
Ashok Kumar
1,
Ashutosh Mishra
1,
Prerak Bhatnagar
1
Affiliations
1 College of Horticulture and Forestry, Jhalawar - 326023, Rajasthan, IN
2 College of Agriculture, Kota – 324001, Rajasthan,, IN
3 Krishi Vigyan Kendra, Kota (Agriculture University, Kota), Kota – 324001, Rajasthan, IN
1 College of Horticulture and Forestry, Jhalawar - 326023, Rajasthan, IN
2 College of Agriculture, Kota – 324001, Rajasthan,, IN
3 Krishi Vigyan Kendra, Kota (Agriculture University, Kota), Kota – 324001, Rajasthan, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 27, No 3&4 (2020), Pagination: 176-187Abstract
Abstract An investigation was carried out under the Department of Fruit Science, College of Horticulture and Forestry, Jhalawar. The experiment was conducted in the pomegranate orchard established under high density planting system at the Krishi Vigyan Kendra, Jhalawar in the near vicinity of the college during July 2018 to December 2018 and again during July 2019 to December 2019. The experiment was laid out in Factorial Randomized Block Design and experiment comprised of 27 treatment combinations consisting of plant growth regulators levels (NAA 0, 50 and 100 ppm and ethrel 0, 150 and 250 ppm) and fertigation levels (0, 75 and 100% recommended dose of fertilizers). Results revealed that maximum mean per cent increase in plant height (10.34), plant spread viz., East-West (7.01) and North-South (6.62), canopy volume (25.87) and leaf area (19.51 cm2) was recorded under F2 (fertigation 100% recommended dose of fertilizers). However, interaction effect of NAA, ethrel and fertigation were found to be relatively higher to their individual effect. In interaction effect maximum mean per cent increase in plant height (13.28), plant spread viz., East-West (8.03) and North-South (7.71), canopy volume (31.72) and leaf area (23.55 cm2) was recorded under N2E1F2 (100 ppm NAA + 150 ppm ethrel + 100% RDF through fertigation).Keywords
Fertigation, High Density Planting, Plant Growth, Pomegranate.References
- Arunadevi A, Kumar SB, Rajangam J, Venkatesan K. Effect of plant growth regulators on growth, yield and quality of acid lime (Citrus aurantifolia Swingle.) var. PKM 1. Journal of Pharmacognosy and Phytochemistry. 2019; 8(3):3438–41.
- Dalal NR, Pawar PS, Taru AS, Tayade SA. Effect of fertigation on yield and quality of sweet orange. International Journal of Chemical Studies. 2019; 7(4):2800–01.
- Devi P, Singh CP, Darmwal M. Drip fertigation and its implication on vegetative growth and leaf nutrient content of mango cv. Pant Sinduri. International Journal of Chemical Studies. 2019; 7(4):1836–9.
- Dogra K, Kumar R, Bakshi P, Kour K. Effect of foliar application of potassium and plant growth regulators on vegetative characteristics of Kinnow mandarin under rain-fed condition. International Journal of Chemical Studies. 2019; 7(2):447–9.
- Goswami JD, Patel NM, Bhadauria HS, Wankhade VR, Effect of plant growth substances on growth, fruit setting and yield of pomegranate cv. Sindhuri. International Journal of Agriculture Science. 2013; 1:332–4.
- Humajahan SV, Patil DR, Patil SN, Reddi VSG, Ambika DS. Effect of fertigation on growth and yield of banana cv. Red banana (Musa AAA). International Journal of Chemical Studies. 2018; 6(6):2186–9.
- Jadhav AR, Dheware RM, Urade PS. Studies on different levels of fertigation on growth and leaf nutrient status of pomegranate (Punica granatum L.) cv. Super Bhagwa. International Journal of Chemical Studies. 2018; 6(5):1580–2.
- Karuna K, Mankar A, Singh G, Ahmad F. Effect of fertigation on growth, phenology and nutrient status in leaves under high density orchard of Citrus sinensis Osbeck cv. Mosambi. International Journal of Current Microbiology and Applied Sciences. 2019; 8(4):202–10. https://doi.org/10.20546/ijcmas.2019.804.021
- Mir MM, Barche S, Singh DB. Effect of plant growth regulators on growth, yield and quality of strawberry (Fragaria x ananassa Duch.) cv. Sweet Charlie. Applied Biological Research. 2004 6:48–51. https://doi.org/10.10 07/BF03244958
- Pareek OP. Pomegranate research report and appraisal. Tech. Doc. No.8, AICFIP on arid zone fruits. 1982.
- Prajapati M, Singh D. Effect of plant growth regulators on flowering, fruit growth and quality of guava (Psidium guajava L.). cv. Allahabad Safeda. International Journal of Current Microbiology and Applied Sciences. 2018; SP-7:3355–61.
- Ramana V, Lakshmi KT, Mukunda L, Gopal K, Sivarama KVNP, Lakshmi NT, Sarada G. Nitrogen and potassium based fertigation response on plant growth, yield and quality of sweet orange (Citrus sinensis Linn. Osbeck) cv. Sathgudi. Research and Review Journal of Agriculture and Allied Sciences. 2014; 3(3):7–10.
- Sahu CK, Patel MK, Panda CM. Effect of pruning and plant growth regulator on plant growth and fruit yield of sapota (Manilkara zapota L.) cv. Cricket Ball. International Journal of Current Microbiology and Applied Sciences. 2018; 7(9):1352–7. https://doi.org/10. 20546/ijcmas. 2018.709.161
- Sindhupriya, V, Auxcilia, J, Soorianathasundaram K. Studies on effect of spacing and fertigation on leaf characters of banana (Musa sp.) cv. quintal nendran (AAB). International Journal of Chemical Studies. 2018; 6(6):1820–4.
- Vanilarasu K, Suresh J, Soorianathasundaram K, Raguchander T, Devrajan K, Kumar K. Impact of biofertigation on growth and yield of banana cv. Ney poovan. International Journal of Chemical Studies. 2018; 6(1):807–10.